Because I'm going to play it a shitload over the next couple of weeks, it deserves a thread!
Since my 360 is in my luggage right now and I won't actually be playing for a few days until I achievement whore up some more of the original - any tips on char creation/starting out in ME2?
[action=Chris]is looking at you, vince and josh![/action]
ME2 character creation is pretty simple. There are way fewer skills and abilities than in the first game, but they all share very short cooldowns so even as a low level Adept or Engineer you'll be flinging your powers around way more often. The inventory mess is much easier to deal with as there's basically no inventory beyond 2 or 3 different kinds of each class of weapon and some armor customization.
Instead of having a Charm/Intimidate score, it's directly based on your level of paragon/renegade. You'll have a leg up coming from the first game on that regard, and you'll also have a few extra levels over someone just starting out. Also, hacking and bypassing security no longer requires point investments; they just have minigames this time that are a little more complex than "durr hit the button as it lights up durr" in the first game.
The "Lift" biotic skill is just broken, kind of like how Singularity was pretty much broken in the previous game. You can also 'arc' biotic abilities around cover; if you've got someone targeted and move your reticle to the side then launch "Warp" or something, the effect will home in on your target and can get around cover that way.
I'm not a huge fan of the 'heat clip' system for 'ammo'; I wish it was sort of a hybrid of the first game's system and the second one's, in that if you fired slowly the clips would dissipate heat like in the first game but if you overheated you'd swap the clip out. Playing an Adept, I'm only allowed two guns and tend to run out of ammo for my Hand Cannon very quickly. Also, if this 'heat clip' system is universal, why the hell do I have specific ammo amounts for each gun, and can't just pull a few clips from my SMG to power the pocket-sized-sniper-rifle Hand Cannon?