Alright so far I'm really digging alot of the amp models in the Axe, especially the ones I'm going to list below and how I use them.
1. The Triaxis sounds, USA Clean, USA Lead 1, USA Lead 2
I love the USA clean sound, it's the Mesa sound I've loved for years and it's replicated perfectly in the model. I love it for all my clean sounds as always
USA Lead 1 sounds a lot like the Triaxis LD2 Green if I back off the treble and presence and up the mids, and sounds more like LD2 Red if I turn those same knobs back up. Being that it's a nice mix of those two modes to my ears, and those were my favorite modes on the Triaxis, this is by far my favorite sound I'm using.
USA Lead 2 is cool, but it's that Mark IIc+ heavy sound, and I know Roger loves it and Metallica loves it, but it's still not my cup of tea for heavy stuff. I do dig it a whole ton for rock sounds and some driven leads.
For both Triaxis heavy tones, I have the graphic EQ set to about where it would be if the Triaxis Dynamic Voice were at 8 or 9, with a nice big scoop which on other amps would be a deathmetal scoop, but on the Triaxis it makes it come to life IMO. The relationship between the amp model and the graphic EQ is PERFECTLY replicated here as it was on the Triaxis and on every Mark III and IV I've ever played.
2. The Rectifier sounds, Recto Orange, Recto Red, and Recto New
I'm really digging the Recto Orange at this point. I have an 808 in front as a clean boost and this thing grinds and gives a ton of chunk. Ballsy and fat, just like a real recto.
I'm not too much into the Recto Red or New at this point, I've found them to be a little much in the gain department, but not having the same, I guess "grit" for lack of a better term that really defines the orange mode for me in this amp.
Also, with the recto modes, I've found the graphic EQ set mildly close to flat with a small sag in the middle works real well. Most of the tone is in the main knobs on this amp and the model is no different. No need for much tweaking in the graphic EQ.
3. The orange mode, the Citrus
I'm loving this mode for subdued over-delayed and reverbed leads and I've noticed the character really changes with the amount of gain. With the gain lower it's a rounder nearly clean sound where you can play softly and you get a clean sound, but hit the strings a little harder and it breaks up into some crispy distortion. Run the knob a little higher and it sustains more, turn it nearly all the way up and the treble jumps out a little making the lead parts sear a bit more. What a dynamic sound from adjusting only one knob!
I'm not digging the Citrus for metal rhythms, but it's not really meant for that anyway
4. The Engl Powerball mode (can't remember the name right now)
I know a lot of you guys don't care much for this mode. I've found it quite useful. By itself, it's not much, but with a drive in front it screams. I'm using the modded 808 in front of it and I'm getting a gain that has a lot of crunch but cuts differently than the Mesa models. It's become my preferred mode for more of the Judas Priest and Megadeth style musical metal rhythm playing, while I like the Recto for more of the chord-based riffs.
5. Other modes I really dig are the Plexi and the Brown.
The Plexi is just that classic Marshall sound. Big and bold, clean and crispy. It just screams Eric Johnson and Stevie Ray Vaughn to me and I'm really digging just toying around with this mode.
The brown is like the metal version of the plexi, modeled after EVH's rig. Great sound too and I love it for Eruption-style tapped leads.
Great stuff all around.
The only modes I'm not really digging are the Fryette modes. Then again, I've really never liked VHTs and I'm totally not into their sound, so that makes sense. The modes do sound spot on the VHTs I've played though, so for those of you that like the VHT sounds, they'll work great for you I'd say.
What do you use and what modes do you gravitate to?