i've got a boss ce-5 that i run into my mark III. i'm tryign to figure out the best place to run it. i'm not really looking for big chorus effects, but more subtle, smooth tones for some lead stuff (kinda similar to rob flynn's lead stuff).
so should i be running it in the loop, or in front? any setting suggestions for a starting point?
Almost without exception you want time-based effects like chorus in the loop. The one exception I could think of would be anything where you want it to change the way the amp distorts - say, Jimi and his Univibe at woodstock, where the thing was pushing his amp in and out of distortion (of course, this was before FX loops were even really standard on amps, so it's tough to say if that was taste or necessity back then).