Yes. I have two 24.75" scale guitars, two 25.5" scale guitars, and one 27" scale guitar.
For rhythm guitar, I can play equally as easily on all three scales. However, for lead guitar, the 25.5" scale is the best. The 24.75" is a little too cramped up around the 22nd fret and, while the 27" scale is decent for lead guitar, it's not as good as the 25.5", I think.
I started playing guitar on a 24.75" and a 25.5" and I never even noticed a difference for the first year.
So yeah, I wouldn't think 24.75" should take too long to adjust to.