I use my Gretsch Pro Jet for metal. The low output pickups give the sound more clean headroom and more clarity. Switching to the neck pickup gives a nice smooth lead tone. The body is very chunky and it's generally a well balanced sound acoustically, with plenty of low end. The Mahogany gives nice sustain and the Rosewood helps keep the low end. The neck is fat and chunky for riffs but it's amazingly fast speed and low action makes it amazing for leads.
In the studios I'll probably end up having a blend of my rig with my Ibanez RG and the Gretsch Pro Jet. The Gretsch will make it on all of the solos though.
Long post - I know my gear really well. Is that bad?
I can explain how the guitar helps compliment my pedals of choice and how the suit the amp so well. Okay I should shut the fuck up.