So far so good. Things that are working so far:
- Superior Drummer
- DMGAudio plug-ins
- Reaper (duh)
- MOTU's hardware drivers
- Ozone 5
That's really all the plugins that I use, but it's nice to open up a full project and have everything work straight away.
Will report back if I find something broken.
Edit: I suppose "updating my DAW" is more like "Updating the Mac I use for recording", but you get the idea.