What version are you guys running on the proper OS, 32-bit or 64-bit?
I don't think any of my plugs are 64, so I'm thinking the former is the way to go.
Any tips besides the obvious RTFM? Studio One has some fucking weird big bug with Sampletank that's really pissing me off, so I quit. I actually want to get shit done, but I swear I fight more with the DAW then I actually finish anything.
Edit: Nothing worse than fighting with the DAW, it's an instant creativity-killer. Last time I tried Sampletank I had a few sniggles getting it working correctly, but I bought Miroslav Philharmonic a while back and their support guys sorted me out. IIRC I ended up just running the Miroslav bits in ST instead of the UI that it ships with. (They're the same thing under the hood.)