Thermionik | Kazrog LLC
Huge fan of Recab. The Serpent (Framus Cobra emulation) I've been using as my main rhythm tone forever rules, and I just fired up two of the new emulations (Mark IIC+ and Soldano Modded Marshall '79 JMP) and they are even more thrash-tastic. Top class stuff. These are all exhaustively modeled after the physical amps, it certainly goes head to head with any software or hardware solution out there and definitely destroys most of the stuff you will find. Unless you have a recording studio, you aren't going to track tones this good.
Go demo it/buy it. Kazrog LLC | Obsessively Engineered Software
I dont know how you guys use amp sims. Some sound great, but they all feel like trash.