I have zero experience with AxeFx or Helix so I got nothing on those 2 for ya. With just a few weeks with the Kemper, I can honestly say I love it. With over 200 factory profiles there is something for everyone, including some killer bass profiles, usable, great sounding, simple, out of the box. Now for the rabbit hole, profiles. Just in Kempers Rig Exchange there are over 14,000 free profiles submitted by Kemper owners, some absolutely suck and some are amazing, I've yet to spend much time on it, there's just too many, lol! Then there's the free and commercial profiles available everywhere. I spent entirely too many hours/days researching these before I bought mine. I've bought some from Replicant and Tonecrate so far and they're amazing profiles. The packs will run from around $15 and up and usually around 20 profiles per pack. I got the Fortin Meshuggah pack from Replicant and it had 50 profiles in it. For me it's not so much as tone-chasing, it was easy with factory profiles to get what I was after, but it's having the option to virtually play through so many different amps that I would not be able to otherwise afford or justify. Will it replace my real amps(tube or otherwise)? Nope. There's still something special about cranking up a real amp. Disclaimer: just my opinion, lol, but when I was looking and trying to find comparisons the Kemper sounded closest to me, the others sound fantastic and are great products, but the Kemper just hit closer to my ears.