The way I have my 11R set up with my monitors, the sound hits the monitors before it ever hits the computer. As such, there is no latency at all. The only unfortunate part about that is the sound coming through my monitors is the guitar tone without the 11R's cab sim, so its fizzy as hell. I don't use track monitoring in Reaper at all due to the zero latency of the 11R, but the tone coming out of the monitors is the compromise. Shit tone while tracking, normal tone during playback. A little give and take, you know?