I've got one permanently in my bass rig and I love the thing. It's really easy to use now that I'm used to it.
You know, if a "sweetened" tuning is making you clash with a keyboard instrument (that is never out of tune), then the "sweetened" tuning is wrong, meaning you're out of tune.Sweetened tunings are awesome, unless you're like me and have a keyboard/Rhodes player in your band. Then you have to make do with normal tuning, as our guitarist found out when his Buzz Feiten'd Washburn clashed horribly with the electric piano during an acoustic practice.
Luckily, with my cello, I have all the room for on-the-fly adjustment in the world. Nevertheless, the experience was scarring!